Application of a high-throughput quantitative PCR system for simultaneous monitoring of SARS-CoV-2 variants and other pathogenic viruses in wastewaterArticle Published on 2022-12-202022-11-15 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] acute respiratory syndrome Alpha variant analyzed application applied assays can be used collected Community coronavirus coronavirus disease COVID-19 delta variant demonstrated detect eight epidemiologically FIVE Health High-throughput qPCR highlighting increase Japan L452R labor-intensive likelihood Mie N501Y nine nucleotide nucleotide substitution pathogenic virus pathogenic viruses Pathogenic viruses, SARS-CoV-2 Patient PCR positive prevalent qPCR quantitative PCR quarantine reported RNA RT-qPCR SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 variant separated Surveillance target tested time-consuming Treatment virus viruses Volume wastewater Wastewater. Yokkaichi [DOI] 10.1016/j.scitotenv.2022.158659 PMC 바로가기
Rapid and universal detection of SARS-CoV-2 and influenza A virus using a reusable dual-channel optic fiber immunosensorArticle Published on 2022-11-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 신종인플루엔자, 치료기술, [키워드] clinical sample colloidal gold Delta demonstrated detect dual-channel optic fiber immunosensor enzyme-linked immunosorbent Evanescent fiber H1N1 H3N2 H7N9 Infectious disease influenza A influenza A virus influenza A virus limit of detection linear mobile phase detection. much higher omicron optical pathogenic viruses platform presenting Rapid Real-time monitoring respond SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 pseudovirus sensitivity specificity Strains Surveillance TCID the epidemic the SARS-CoV-2 the spike protein variants viruses [DOI] 10.1002/jmv.28015 PMC 바로가기
Understanding and combating COVID-19 using the biology and chemistry of SARS-CoV-2Article Published on 2022-11-012022-11-15 Journal: Bioprocess and biosystems engineering [Category] SARS, 치료기술, [키워드] ACE acute respiratory syndrome angiotensin-converting enzyme 2 Angiotensin-converting enzyme 2 (ACE2) Asymptomatic binding caused combating contributed coronavirus coronavirus disease COVID-19 enzyme high affinity host receptor hydrophobic Infection Interaction lead to fatality Like molnupiravir Mutation Nanotechnology omicron pandemic pathogenic viruses PAXLOVID™ provide quercetin Remdesivir responsible SARS-CoV-2 spike glycoprotein suggested Transmissibility understanding vaccine. Vaccines viability virus [DOI] 10.1007/s00449-022-02788-8 PMC 바로가기
Molecular Docking and In-Silico Analysis of Natural Biomolecules against Dengue, Ebola, Zika, SARS-CoV-2 Variants of Concern and Monkeypox VirusArticle Published on 2022-09-222022-11-15 Journal: International Journal of Molecular Sciences [Category] SARS, 변종, 진단, 치료제, [키워드] Amino acid AMP AMPs antimicrobial peptide Antiviral antiviral drug Antiviral treatment AutoDock vina B.1.617.2 Bacterial bacterial AMPs binding energy Biomolecule biomolecules Cell cell receptor cell surface receptors concern Control Dengue dengue virus determine develop docking docking score Ebola Ebola virus Effective vaccines envelope protein Evolution in silico increase in indicated Modification molecular molecular docking Monkeypox monkeypox. mutant natural Occurrence P.1 pathogenic viruses positive proline Protein receptors SARS-CoV-2 Secondary Metabolite specific neutralizing antibody tested the SARS-CoV-2 the spike protein therapeutic agents variant variants of SARS-CoV-2 viral cell viral surface virus virus was performed Zika Zika virus [DOI] 10.3390/ijms231911131 PMC 바로가기
Trafficked Malayan pangolins contain viral pathogens of humans밀매된 말레이 천산갑에는 인간의 바이러스성 병원체가 포함되어 있습니다.Article Published on 2022-08-012022-09-11 Journal: Nature Microbiology [Category] Fulltext, SARS, 치료기술, [키워드] bats China coronavirus coronavirus FIVE genomic sequence Human Hunnivirus identify mammal mammals Orthopneumovirus pangolin pangolins pathogenic viruses Pestivirus reported respiratory syncytial virus rotavirus sequence sequenced sequences these viruses vertebrates viral pathogen virus viruses wild animal wildlife [DOI] 10.1038/s41564-022-01181-1 PMC 바로가기 [Article Type] Article
Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses신종 바이러스에 대해 활성을 나타내는 광범위한 항바이러스제로서 타고난 면역 신호의 인핸서 식별Article Published on 2022-07-212022-09-11 Journal: Cell chemical biology [Category] COVID19(2023년), SARS, 치료제, [키워드] active against acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antiviral antiviral activity boost broad-spectrum antiviral broad-spectrum antivirals Compound coronavirus Defense dependent on Drug screening emerging viruses enhancer Factors Gilteritinib identifying Immunity immunomodulatory molecules immunostimulatory IMPROVE increasingly Infection Innate innate immune innate immune activation Innate immunity innate response interferon interferon regulatory factor interferon regulatory factors. IRF7 IRFs Kinase inhibitor kinase inhibitors library nuclear translocation outbreak Pandemics pathogenic virus pathogenic viruses Pathogens proof proof of concept Regulatory RNA viruses SARS-CoV-2 screened severe acute respiratory syndrome Coronavirus Signaling viral infection virus [DOI] 10.1016/j.chembiol.2022.05.009 PMC 바로가기 [Article Type] Article
Detection of Ancient Viruses and Long-Term Viral Evolution고대 바이러스의 탐지 및 장기간의 바이러스 진화Review Published on 2022-06-182022-09-11 Journal: Viruses [Category] 치료기술, [키워드] analyzed ancient DNA ancient RNA ancient virome ancient virus approach bioinformatics complex COVID-19 outbreak detectable detection events human population NGS Pandemics past pathogenic pathogenic virus pathogenic viruses PCR preserved recent RNA Sequencing specimen TDRP tissues unique Usage viral DNA viral evolution viral evolution. viral genome viral genomes virus [DOI] 10.3390/v14061336 PMC 바로가기 [Article Type] Review
Direct and quantitative capture of viable bacteriophages from experimentally contaminated indoor air: A model for the study of airborne vertebrate viruses including SARS-CoV-2실험적으로 오염된 실내 공기에서 살아있는 박테리오파지의 직접 및 정량 캡처: SARS-CoV-2를 포함한 공기 중 척추동물 바이러스 연구 모델Article Published on 2022-02-012022-09-11 Journal: Journal of Applied Microbiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] addressed aerobiology aerosolization agar air decontamination airborne viruses allergen allergens Bacteria bacteriophage bacteriophages coliphage MS2 construction contaminated surfaces coronavirus SARS-CoV-2 Direct Ebola ENhance filtration Health HEPA Host implication inactivation indoor air Influenza MS2 Particle particulates pathogen pathogenic pathogenic viruses Pathogens phage phage Phi6. phages Quantitative reported Safe SARS-CoV-2 Significance Surrogates survival tested Transmission UV light virus virus [DOI] 10.1111/jam.15262 PMC 바로가기 [Article Type] Article
A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune–epithelial interface420 Published on 2021-12-282022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, [키워드] acute respiratory syndrome age B cells Blood children Coronavirus-2 COVID-19 COVID-19 patients cross-talk Cytokine storm deviation Ebola elicit encodes epithelia epithelial epithelial cell Express Factors fraction gene cluster hallmark healthy children Immune cell immune cells immune dysregulation induce infected with SARS-CoV-2 Inflammatory inflammatory phenotype influenza A initial Interaction interferon lung manifestation monocyte multiorgan failure myeloid cell nonstructural proteins pathogenic viruses Patient Perturbation Pneumonia Protein provide provoke reported SARS-CoV-2 SARS-CoV-2 protein severe COVID-19 severe disease Significance spike systemic inflammation transcriptional transduced virus [DOI] 10.1073/pnas.2116853118 PMC 바로가기 [Article Type] 420
How Antibodies Recognize Pathogenic Viruses: Structural Correlates of Antibody Neutralization of HIV-1, SARS-CoV-2, and ZikaReview Published on 2021-10-192022-10-28 Journal: Viruses [Category] COVID-19, MERS, SARS, [키워드] antibody approach can be used contributed COVID-19 pandemic Cryo-electron microscopy determine Determining Ebola effective vaccine elicited Epidemic Epidemics epitope example H1N1 pandemic HIV-1 identify Infection MERS Molecular biology monoclonal antibodies morbidity and mortality neutralization pathogenic viruses reducing Safe SARS-CoV-2 small molecule inhibitor structural biology vaccination Vaccines viral epidemics viral infection Viral protein virus virus viruses X-ray crystallography Zika [DOI] 10.3390/v13102106 PMC 바로가기 [Article Type] Review